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Protein Coding Gene : Fetub fetuin beta
Primary Identifier  MGI:1890221 Organism  mouse, laboratory
Chromosome  16 NCBI Gene Number  59083
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables metalloendopeptidase inhibitor activity. Involved in binding activity of sperm to zona pellucida and negative regulation of endopeptidase activity. Predicted to be located in extracellular space. Predicted to be active in extracellular region. Is expressed in several structures, including genitourinary system; jaw bone; liver; muscle tissue; and olfactory epithelium. Orthologous to human FETUB (fetuin B).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit female infertility due to premature hardening of the zona pellucida. [provided by MGI curators]
  • synonyms:
  • 2310011O17Rik,
  • Fetub,
  • MGI:2146393,
  • MGI:1915165,
  • expressed sequence AI255764,
  • AI255764,
  • RIKEN cDNA 2310011O17 gene,
  • fetuin beta,
  • D17980
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