Primary Identifier | MGI:2441849 | Organism | mouse, laboratory |
Chromosome | 16 | NCBI Gene Number | 210126 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable metal ion binding activity. Predicted to be involved in cell-cell adhesion. Predicted to be located in cytosol. Predicted to be active in focal adhesion and stress fiber. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system; and musculoskeletal system. Human ortholog(s) of this gene implicated in acute myeloid leukemia. Orthologous to human LPP (LIM domain containing preferred translocation partner in lipoma). PHENOTYPE: Gene disruption results in fertility problems involving females but not males. Migration and survival of MEFs are also abnormal. [provided by MGI curators] |