| Primary Identifier | MGI:1276109 | Organism | mouse, laboratory |
| Chromosome | 16 | NCBI Gene Number | 12737 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables identical protein binding activity. Involved in calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules; cell junction maintenance; and establishment of skin barrier. Located in apical plasma membrane; bicellular tight junction; and lateral plasma membrane. Is expressed in several structures, including alimentary system; axial skeleton; brain; metanephros; and skin. Human ortholog(s) of this gene implicated in Crohn's disease and atopic dermatitis. Orthologous to human CLDN1 (claudin 1). PHENOTYPE: Animals homozygous for a mutation in this gene have wrinkled skin and die within 1 day after birth. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
