| Primary Identifier | MGI:104975 | Organism | mouse, laboratory |
| Chromosome | 16 | NCBI Gene Number | 16180 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables interleukin-1 receptor activity and interleukin-33 receptor activity. Involved in several processes, including interleukin-33-mediated signaling pathway; positive regulation of cytokine production; and regulation of synapse assembly. Acts upstream of or within cytokine-mediated signaling pathway. Is active in glutamatergic synapse. Is expressed in several structures, including aorta-gonad-mesonephros; brain ventricle and choroid plexus; forebrain; renal calyx; and ventral grey horn. Orthologous to human IL1RAP (interleukin 1 receptor accessory protein). PHENOTYPE: Mice homozygous for a knock-out allele are viable, fertile and grossly normal but show no biological response to IL-1. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
