Primary Identifier | MGI:2677164 | Organism | mouse, laboratory |
Chromosome | 16 | NCBI Gene Number | 239790 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables signaling receptor binding activity. Acts upstream of or within several processes, including endochondral bone growth; negative regulation of D-glucose import; and negative regulation of osteoblast differentiation. Located in extracellular space. Is expressed in genitourinary system; heart; musculature; and skeleton. Orthologous to human OSTN (osteocrin). PHENOTYPE: Mice homozygous for a null allele display impaired exercise endurance and impaired muscle adaptation to exercise. [provided by MGI curators] |