Primary Identifier | MGI:2444068 | Organism | mouse, laboratory |
Chromosome | 16 | NCBI Gene Number | 268878 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ATPase-coupled monoatomic cation transmembrane transporter activity and polyamine transmembrane transporter activity. Predicted to be involved in intracellular calcium ion homeostasis and polyamine transmembrane transport. Predicted to be located in membrane. Predicted to be active in late endosome membrane. Is expressed in several structures, including dentate gyrus subgranular zone; lung; musculature; sensory organ; and urinary system. Orthologous to human ATP13A5 (ATPase 13A5). PHENOTYPE: Homozygous mutant mice show a decreased mean percentage of natural killer cells when compared with controls. Male homozygous mutant mice exhibit impaired sensorimotor gating/attention during prepulse inhibition testing. [provided by MGI curators] |