| Primary Identifier | MGI:1913311 | Organism | mouse, laboratory |
| Chromosome | 16 | NCBI Gene Number | 66061 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable dynein intermediate chain binding activity. Predicted to be involved in intraciliary retrograde transport and regulation of intraciliary retrograde transport. Predicted to be located in ciliary base; cytoskeleton; and dynein axonemal particle. Predicted to be part of cytoplasmic dynein complex. Predicted to be active in cytoplasm. Is expressed in embryo and forelimb bud. Human ortholog(s) of this gene implicated in asphyxiating thoracic dystrophy. Orthologous to human DYNLT2B (dynein light chain Tctex-type 2B). PHENOTYPE: Male mice homozygous for a null allele display male infertility with oligoasthenozoospermia, defects in axoneme formation, reduced numbers of elongated spermatids, and defects in sperm flagellum morphology. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
