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Protein Coding Gene : Iqcg IQ motif containing G
Primary Identifier  MGI:1916957 Organism  mouse, laboratory
Chromosome  16 NCBI Gene Number  69707
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables calmodulin binding activity. Involved in sperm axoneme assembly. Located in cytoplasm; manchette; and sperm flagellum. Is active in cytosol. Is expressed in brain; lung epithelium; and nose. Orthologous to human IQCG (IQ motif containing G).
PHENOTYPE: Homozygous male mice are infertile and have very low epididymal sperm concentration with low motility, predominantly appearing as sperm heads without tails or with short tails. [provided by MGI curators]
  • synonyms:
  • early spermiogenesis defective 12d,
  • 2400003L07Rik,
  • stubby12d,
  • G1-374-12,
  • IQ motif containing G,
  • esgd12d,
  • repro1,
  • RIKEN cDNA 2400003L07 gene,
  • Iqcg,
  • MGI:3050605
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