| Primary Identifier | MGI:1933117 | Organism | mouse, laboratory |
| Chromosome | 16 | NCBI Gene Number | 80285 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including ADP-D-ribose binding activity; NAD+-protein ADP-ribosyltransferase activity; and STAT family protein binding activity. Involved in positive regulation of type II interferon-mediated signaling pathway. Predicted to be located in several cellular components, including mitochondrion; nucleoplasm; and site of DNA damage. Predicted to be part of protein-containing complex. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; brain; hemolymphoid system; nasal cavity; and urinary system. Orthologous to human PARP9 (poly(ADP-ribose) polymerase family member 9). PHENOTYPE: Mice homozygous for a null allele exhibit higher viral titers in the liver, lungs, spleen, and brains, and decreased type I IFN production in response to infection with RNA virus. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
