Primary Identifier | MGI:103560 | Organism | mouse, laboratory |
Chromosome | 16 | NCBI Gene Number | 16646 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable nuclear import signal receptor activity and nuclear localization sequence binding activity. Involved in postsynapse to nucleus signaling pathway. Acts upstream of or within several processes, including NLS-bearing protein import into nucleus; satellite cell activation involved in skeletal muscle regeneration; and skeletal muscle satellite cell proliferation. Is active in glutamatergic synapse and postsynaptic density. Is expressed in several structures, including central nervous system; genitourinary system; gut; integumental system; and sensory organ. Orthologous to human KPNA1 (karyopherin subunit alpha 1). PHENOTYPE: Mice homozygous for a gene trap allele do not display any nervous system or behavioral abnormalities. [provided by MGI curators] |