Primary Identifier | MGI:1930150 | Organism | mouse, laboratory |
Chromosome | 16 | NCBI Gene Number | 64082 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables cAMP binding activity. Acts upstream of or within regulation of heart rate; regulation of membrane potential; and sinoatrial node cell development. Located in membrane. Is expressed in several structures, including gut; heart and pericardium; limb; trunk; and urogenital sinus. Orthologous to human POPDC2 (popeye domain cAMP effector 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit sinus brachycardia in response to physical or mental stress and catecholamines with a compact sinoatrial node. [provided by MGI curators] |