| Primary Identifier | MGI:1915146 | Organism | mouse, laboratory |
| Chromosome | 16 | NCBI Gene Number | 67896 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables fibronectin binding activity and heparin binding activity. Acts upstream of or within extracellular matrix organization; positive regulation of cell-substrate adhesion; and response to bacterium. Located in basement membrane and interstitial matrix. Is expressed in several structures, including alimentary system; brain; cardiovascular system; limb cartilage condensation; and musculoskeletal system. Orthologous to human CCDC80 (coiled-coil domain containing 80). PHENOTYPE: Mice homozygous for a null allele exhibit increased adiposity, hyperglycemia, glucose intolerance, impaired insulin secretion, and altered energy intake and expenditure when fed a high-fat diet. Mice homozygous for a different null allele develop thyroid adenomas and ovarian carcinomas. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
