Primary Identifier | MGI:1888505 | Organism | mouse, laboratory |
Chromosome | 16 | NCBI Gene Number | 57263 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable hormone activity. Acts upstream of or within response to bacterium. Located in extracellular region. Is expressed in several structures, including brown fat; genitourinary system; intestine; liver; and spleen. Orthologous to human RETNLB (resistin like beta). PHENOTYPE: Homozygous mutation of this gene on a C57BL/6 background provides protection from DSS-induced colitis while on an FVB/N background, mice are more susceptible to AOM/DSS-induced colon tumors. [provided by MGI curators] |