Primary Identifier | MGI:2444583 | Organism | mouse, laboratory |
Chromosome | 16 | NCBI Gene Number | 320712 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables collagen binding activity and heparin binding activity. Acts upstream of or within extracellular matrix organization and positive regulation of cell-substrate adhesion. Located in interstitial matrix. Is expressed in several structures, including embryo mesenchyme; gut; male reproductive gland or organ; nose; and telencephalon. Orthologous to human ABI3BP (ABI family member 3 binding protein). PHENOTYPE: Homozygotes for a null allele show no major changes in anxiety, depression-like behavior, olfactory function or tumor incidence. Homozygotes for a different null allele show reduced cardiac progenitor cell (CPC) differentiation, increased CPC proliferation, and susceptibility to myocardial injury. [provided by MGI curators] |