| Primary Identifier | MGI:88463 | Organism | mouse, laboratory |
| Chromosome | 16 | NCBI Gene Number | 12837 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be an extracellular matrix structural constituent conferring tensile strength. Acts upstream of or within camera-type eye morphogenesis; endothelial cell proliferation; and positive regulation of cell-substrate adhesion. Located in collagen-containing extracellular matrix and extracellular space. Is expressed in several structures, including brain; craniocervical region bone; gut; heart; and limb mesenchyme. Orthologous to human COL8A1 (collagen type VIII alpha 1 chain). PHENOTYPE: Mutation of this gene causes cornea abnormalities that include increased depth of the anterior chamber and a thinner corneal stroma and Descemet's membrane. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
