Primary Identifier | MGI:99842 | Organism | mouse, laboratory |
Chromosome | 16 | NCBI Gene Number | 15557 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable G protein-coupled serotonin receptor activity; neurotransmitter receptor activity; and serotonin binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; adenylate cyclase-inhibiting serotonin receptor signaling pathway; and chemical synaptic transmission. Predicted to be active in dendrite and plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and mammary gland. Orthologous to human HTR1F (5-hydroxytryptamine receptor 1F). PHENOTYPE: Mice homozygous for disruptions in this gene display decreased temperature sensitivity and physiological abnormalities in nerve fibers. [provided by MGI curators] |