| Primary Identifier | MGI:1309463 | Organism | mouse, laboratory |
| Chromosome | 16 | NCBI Gene Number | 110920 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ATP hydrolysis activity; heat shock protein binding activity; and protein folding chaperone. Predicted to be involved in chaperone cofactor-dependent protein refolding and protein refolding. Predicted to be located in endoplasmic reticulum. Predicted to be active in cytosol; nucleus; and plasma membrane. Is expressed in several structures, including genitourinary system; gut; nervous system; sensory organ; and thymus. Orthologous to human HSPA13 (heat shock protein family A (Hsp70) member 13). PHENOTYPE: Mice homozygous for a conditional allele in immune cells exhibit reduction in plasmablast, plasma cell, and antibodies induced LPS or sheep red blood cells, and reduced susceptibility to systemic lupus erythematosus. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
