| Primary Identifier | MGI:1914992 | Organism | mouse, laboratory |
| Chromosome | 16 | NCBI Gene Number | 67742 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable phosphotyrosine residue binding activity. Involved in negative regulation of B cell activation; negative regulation of adaptive immune response; and negative regulation of peptidyl-tyrosine phosphorylation. Located in cytosol and nucleus. Is expressed in several structures, including cardiovascular system; embryo mesenchyme; nervous system; sensory organ; and surface ectoderm. Orthologous to human SAMSN1 (SAM domain, SH3 domain and nuclear localization signals 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit enhanced adaptive immunity. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
