Primary Identifier | MGI:2676840 | Organism | mouse, laboratory |
Chromosome | 16 | NCBI Gene Number | 387173 |
Mgi Type | miRNA gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within several processes, including cellular response to cytokine stimulus; cellular response to dexamethasone stimulus; and regulation of gene expression. Is expressed in cumulus of mature follicle; early conceptus; and oocyte. Used to study lymphoma. Human ortholog(s) of this gene implicated in colon adenocarcinoma; hepatocellular carcinoma; oropharynx cancer; and type 1 diabetes mellitus. Orthologous to human MIR155 (microRNA 155). PHENOTYPE: Mice homozygous for this loss-of-function/reporter allele are viable and fertile, with the lacZ reporter allowing detection of bic/Mirn155 promoter transcriptional activity. [provided by MGI curators] |