Primary Identifier | MGI:95610 | Organism | mouse, laboratory |
Chromosome | 16 | NCBI Gene Number | 14390 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and chromatin binding activity. Acts upstream of or within blastocyst formation; negative regulation of megakaryocyte differentiation; and negative regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Orthologous to human GABPA (GA binding protein transcription factor subunit alpha). PHENOTYPE: Mice homozygous for disruptions in this gene die early in embryonic development. [provided by MGI curators] |