Primary Identifier | MGI:1921362 | Organism | mouse, laboratory |
Chromosome | 16 | NCBI Gene Number | 74112 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables histone H2A deubiquitinase activity. Involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; early embryo; genitourinary system; nervous system; and sensory organ. Orthologous to human USP16 (ubiquitin specific peptidase 16). PHENOTYPE: Mice homozygous for a transgenic gene disruption exhibit embryonic lethality at E6. [provided by MGI curators] |