| Primary Identifier | MGI:1913828 | Organism | mouse, laboratory |
| Chromosome | 16 | NCBI Gene Number | 66578 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein-macromolecule adaptor activity. Acts upstream of or within chromatin remodeling; chromosome segregation; and protein localization to chromosome, centromeric region. Located in chromosome, centromeric region. Part of CENP-A recruiting complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Orthologous to human MIS18A (MIS18 kinetochore protein A). PHENOTYPE: Mice homozygous for a knock-out allele exhibit embryonic lethality between implantation and placentation, reduced growth of the inner cell mass and degeneration, increased apoptosis, decreased DNA methylation, and abnormal mitosis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
