| Primary Identifier | MGI:1924287 | Organism | mouse, laboratory |
| Chromosome | 16 | NCBI Gene Number | 77037 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity; melanocortin receptor binding activity; and signaling receptor regulator activity. Acts upstream of or within brown fat cell differentiation. Predicted to be located in intracellular membrane-bounded organelle. Predicted to be active in endoplasmic reticulum and plasma membrane. Is expressed in several structures, including brain; exocrine system; olfactory epithelium; respiratory system; and urinary system. Used to study adrenal gland disease. Human ortholog(s) of this gene implicated in familial glucocorticoid deficiency. Orthologous to human MRAP (melanocortin 2 receptor accessory protein). PHENOTYPE: Mice homozygous for a null allele exhibit neonatal lethality associated with failure of lungs to inflate, small adrenal glands, thickened adrenal casule due to hyperplasia and glucocorticoid deficiency symptoms. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
