Primary Identifier | MGI:2146468 | Organism | mouse, laboratory |
Chromosome | 16 | NCBI Gene Number | 207932 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be involved in maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in fibrillar center. Predicted to be active in nucleolus. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and sensory organ. Orthologous to human URB1 (URB1 ribosome biogenesis homolog). PHENOTYPE: Mice homozygous for a null allele exhibit absent blastocoele, arrest at the morula stage at E4.5, and die. [provided by MGI curators] |