Primary Identifier | MGI:1355334 | Organism | mouse, laboratory |
Chromosome | 16 | NCBI Gene Number | 50914 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and E-box binding activity. Involved in oligodendrocyte development. Acts upstream of or within neuron fate commitment. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; embryo mesenchyme; future diencephalon; sensory organ; and testis. Orthologous to human OLIG1 (oligodendrocyte transcription factor 1). PHENOTYPE: Homozygous mutation of this gene results in impaired maturation of oligodendrocytes. [provided by MGI curators] |