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Protein Coding Gene : Setd4 SET domain containing 4

Primary Identifier  MGI:2136890 Organism  mouse, laboratory
Chromosome  16 NCBI Gene Number  224440
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables histone H3K4 methyltransferase activity. Involved in several processes, including positive regulation of cytokine production; positive regulation of inflammatory response; and regulation of cell proliferation in bone marrow. Predicted to be located in cytosol and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and sensory organ. Orthologous to human SETD4 (SET domain containing 4).
PHENOTYPE: Mice homozygous for a null mutation display reduced expression of inflammatory cytokines by macrophages. [provided by MGI curators]
  • synonyms:
  • SET domain containing 4,
  • open reading frame 21,
  • MGI:2449622,
  • Setd4,
  • AY037804,
  • cDNA sequence AY037804,
  • ORF21

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

10 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

2 Driver For