| Primary Identifier | MGI:2181192 | Organism | mouse, laboratory |
| Chromosome | 16 | NCBI Gene Number | 170765 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in heart development; negative regulation of transcription by RNA polymerase II; and pharyngeal system development. Acts upstream of or within negative regulation of cell population proliferation. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; branchial arch; genitourinary system; nervous system; and sensory organ. Orthologous to human RIPPLY3 (ripply transcriptional repressor 3). PHENOTYPE: Homozygotes for a reporter allele show complete neonatal lethality, abnormal development of the pharyngeal apparatus and its derivatives including ectopic formation of the thymus and the parathyroid gland, and cardiovascular defects such as deletion of the aortic arch and misshapen great vessels. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
