| Primary Identifier | MGI:1860263 | Organism | mouse, laboratory |
| Chromosome | 16 | NCBI Gene Number | 56088 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables proteasome binding activity. Acts upstream of or within cerebellar granule cell precursor proliferation and proteasome core complex assembly. Predicted to be located in Golgi apparatus; cytosol; and nucleoplasm. Predicted to be part of protein folding chaperone complex. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and sensory organ. Orthologous to human PSMG1 (proteasome assembly chaperone 1). PHENOTYPE: Mice homozygous for a knock-out allele die by E6.5. Mice homozygous for a conditional allele activated in the brain exhibit abnormal brain development, neurological defects, and die by P21. Mice homozygous for a conditional allele activated in the liver exhibit premature hepatocyte senescence. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
