| Primary Identifier | MGI:1196281 | Organism | mouse, laboratory |
| Chromosome | 16 | NCBI Gene Number | 13508 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables netrin receptor binding activity and protein tyrosine kinase binding activity. Involved in several processes, including netrin-activated signaling pathway; neuron development; and positive regulation of axon extension involved in axon guidance. Acts upstream of or within several processes, including dendrite development; glutamatergic synaptic transmission; and post-embryonic retina morphogenesis in camera-type eye. Located in several cellular components, including dendrite; growth cone; and neuronal cell body. Is expressed in several structures, including central nervous system; peripheral nervous system; sensory organ; skin; and testis. Orthologous to human DSCAM (DS cell adhesion molecule). PHENOTYPE: Mice homozygous for a null allele exhibit background-sensitive perinatal lethality associated with respiratory distress, altered C4 ventral root and pre-inspiratory neuron signaling, and abnormal response to hypercapnia. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
