Primary Identifier | MGI:1270150 | Organism | mouse, laboratory |
Chromosome | 16 | NCBI Gene Number | 52793 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable cytokine activity. Involved in insulin secretion. Predicted to be located in nuclear envelope lumen. Predicted to be active in extracellular space. Is expressed in several structures, including branchial arch; heart; stomach; surface ectoderm; and testis. Orthologous to human FAM3B (FAM3 metabolism regulating signaling molecule B). PHENOTYPE: Mice homozygous for a deletion of this gene display elevated blood glucose in glucose tolerance tests and elevated blood insulin after glucose injection, probably due to impaired insulin clearance. [provided by MGI curators] |