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Protein Coding Gene : Fam3b FAM3 metabolism regulating signaling molecule B

Primary Identifier  MGI:1270150 Organism  mouse, laboratory
Chromosome  16 NCBI Gene Number  52793
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable cytokine activity. Involved in insulin secretion. Predicted to be located in nuclear envelope lumen. Predicted to be active in extracellular space. Is expressed in several structures, including branchial arch; heart; stomach; surface ectoderm; and testis. Orthologous to human FAM3B (FAM3 metabolism regulating signaling molecule B).
PHENOTYPE: Mice homozygous for a deletion of this gene display elevated blood glucose in glucose tolerance tests and elevated blood insulin after glucose injection, probably due to impaired insulin clearance. [provided by MGI curators]
  • synonyms:
  • Pander,
  • RIKEN cDNA 9030624C24 gene,
  • open reading frame 9,
  • MGI:1923006,
  • DNA segment, Chr 16, Johns Hopkins University 19, expressed,
  • 9030624C24Rik,
  • D16Jhu19e,
  • FAM3 metabolism regulating signaling molecule B,
  • DNA segment, Chr 16, Johns Hopkins University 19,
  • ORF9,
  • Fam3b

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

6 Involved In Mutations

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0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For