Primary Identifier | MGI:1927240 | Organism | mouse, laboratory |
Chromosome | 16 | NCBI Gene Number | 114565 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; POZ domain binding activity; and methyl-CpG binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Is expressed in brain; early conceptus; genitourinary system; and surface ectoderm. Orthologous to human ZBTB21 (zinc finger and BTB domain containing 21). PHENOTYPE: Homozygous null mice show little to no synaptic or cognitive deficits. [provided by MGI curators] |