Primary Identifier | MGI:96918 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 17171 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables angiotensin receptor activity and peptide binding activity. Involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway and angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure. Acts upstream of or within positive regulation of canonical NF-kappaB signal transduction and regulation of inflammatory response. Predicted to be located in cell surface. Predicted to be active in plasma membrane. Is expressed in several structures, including brain; extraembryonic component; gut; reproductive system; and spleen. Orthologous to human MAS1 (MAS1 proto-oncogene, G protein-coupled receptor). PHENOTYPE: Mice homozygous for disruptions in this gene show enhanced long term potentiation and higher levels of anxiety. They are otherwise normal and fertile. [provided by MGI curators] |