Primary Identifier | MGI:1916049 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 68799 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables identical protein binding activity. Involved in positive regulation of DNA-templated transcription and signal transduction. Acts upstream of or within BMP signaling pathway and cell adhesion. Located in endoplasmic reticulum-Golgi intermediate compartment and plasma membrane. Is expressed in several structures, including future brain; gut; musculoskeletal system; nervous system; and sensory organ. Orthologous to human RGMB (repulsive guidance molecule BMP co-receptor b). PHENOTYPE: Mice homozygous for a knock-out allele exhibit lethality at 2 to 3 weeks after birth. [provided by MGI curators] |