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Protein Coding Gene : Rgmb repulsive guidance molecule family member B

Primary Identifier  MGI:1916049 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  68799
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables identical protein binding activity. Involved in positive regulation of DNA-templated transcription and signal transduction. Acts upstream of or within BMP signaling pathway and cell adhesion. Located in endoplasmic reticulum-Golgi intermediate compartment and plasma membrane. Is expressed in several structures, including future brain; gut; musculoskeletal system; nervous system; and sensory organ. Orthologous to human RGMB (repulsive guidance molecule BMP co-receptor b).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit lethality at 2 to 3 weeks after birth. [provided by MGI curators]
  • synonyms:
  • 1110059F19Rik,
  • RIKEN cDNA 1110059F19 gene,
  • RGM domain family, member B,
  • DRAGON,
  • Rgmb,
  • repulsive guidance molecule family member B

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For