| Primary Identifier | MGI:1278319 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 14289 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables N-formyl peptide receptor activity and amyloid-beta binding activity. Involved in cellular response to amyloid-beta; positive chemotaxis; and positive regulation of superoxide anion generation. Acts upstream of or within phospholipase C-activating G protein-coupled receptor signaling pathway. Predicted to be located in cytoplasm. Predicted to be active in plasma membrane. Orthologous to human FPR2 (formyl peptide receptor 2). PHENOTYPE: Mice homozygous for a targeted reporter allele exhibit altered leukocyte responses and experimentally induced inflammation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
