Primary Identifier | MGI:2443938 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 240047 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable metalloendopeptidase activity and peptidase activator activity. Acts upstream of or within hard palate development. Located in plasma membrane. Is expressed in heart; palatal shelf; palatal shelf epithelium; palatal shelf mesenchyme; and trigeminal ganglion. Orthologous to human MMP25 (matrix metallopeptidase 25). PHENOTYPE: Mice homozygous for a null mutation display impaired angiogenic sprouting in the brain and impaired innate immune responses. [provided by MGI curators] |