Primary Identifier | MGI:2677480 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 386612 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable RNA binding activity. Predicted to be involved in central nervous system development and mRNA export from nucleus. Predicted to be located in nuclear speck. Predicted to be part of THO complex part of transcription export complex. Predicted to colocalize with chromosome, telomeric region. Orthologous to human THOC6 (THO complex subunit 6). PHENOTYPE: Mice with biallelic loss of function are embryonic lethal by E11.5. Embryos are smaller, show developmental delay by E9.5, and show thinner epithelium in the telencephalic vesicles. [provided by MGI curators] |