| Primary Identifier | MGI:1913955 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 66705 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA binding activity and deoxyribonuclease I activity. Acts upstream of or within DNA catabolic process; corneocyte development; and hair follicle development. Predicted to be located in cytoplasm and extracellular region. Predicted to be active in nucleus. Is expressed in several structures, including Harderian gland; alimentary system; brain; genitourinary system; and hemolymphoid system. Orthologous to human DNASE1L2 (deoxyribonuclease 1 like 2). PHENOTYPE: Mice homozygous for disruption in this gene retain DNA in corneocytes of the hair and some other structures. Mice homozygous for a different knock-out allele exhibit decreased grip strength, decreased body weight, abnormal homeostasis and abnormal skeleton. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
