| Primary Identifier | MGI:109530 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 13560 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA binding activity. Involved in regulation of cell cycle process. Acts upstream of or within DNA replication; positive regulation of transcription by RNA polymerase II; and regulation of mitotic cell cycle, embryonic. Located in nucleus and spindle. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human E4F1 (E4F transcription factor 1). PHENOTYPE: Homozygous null mice display early embryonic lethality with mitotic progression failure and increased apoptosis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
