Primary Identifier | MGI:1914328 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 67078 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables ADP phosphatase activity; magnesium ion binding activity; and phosphatase activity. Involved in glycerol biosynthetic process and glycerophospholipid metabolic process. Predicted to be active in cytoplasm. Is expressed in allantois; amnion; chorion; embryo; and yolk sac. Orthologous to human PGP (phosphoglycolate phosphatase). PHENOTYPE: Mice homozygous for a knock-out allele are embryonic lethal and show embryonic growth retardation, delayed embryo turning, abnormal somitogenesis, hemorrhages, reduced blood vessel density in the placental labyrinth, and cell proliferation defects under normoxic conditions. [provided by MGI curators] |