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Protein Coding Gene : Mlst8 MTOR associated protein, LST8 homolog (S. cerevisiae)
Primary Identifier  MGI:1929514 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  56716
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable protein serine/threonine kinase activator activity. Acts upstream of or within positive regulation of actin filament polymerization and positive regulation of peptidyl-tyrosine phosphorylation. Part of TORC1 complex. Is expressed in central nervous system and retina. Orthologous to human MLST8 (MTOR associated protein, LST8 homolog).
PHENOTYPE: Mice homozygous for a null mutation exhibit lethality around E10.5 and abnormal yolk sac vasculature, brain development and heart development. [provided by MGI curators]
  • synonyms:
  • Gbl,
  • expressed sequence AI505104,
  • RIKEN cDNA 0610033N12 gene,
  • expressed sequence AI851821,
  • AI505104,
  • expressed sequence AA409454,
  • Mlst8,
  • 0610033N12Rik,
  • mLST8,
  • MTOR associated protein, LST8 homolog (S. cerevisiae),
  • AA409454,
  • MGI:1917593,
  • MGI:2146886,
  • MGI:2146940,
  • AI851821,
  • MGI:2146758,
  • G protein beta subunit-like
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