Primary Identifier | MGI:1341881 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 20974 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables SH2 domain binding activity. Involved in positive regulation of transporter activity; regulated exocytosis; and regulation of synaptic vesicle priming. Located in synapse. Is active in neuromuscular junction and synaptic vesicle. Is expressed in several structures, including central nervous system; eye; and peripheral nervous system ganglion. Orthologous to human SYNGR3 (synaptogyrin 3). PHENOTYPE: Heterozygous knockout prevents the neurological phenotypes of pathogenic forms of microtubule-associated protein tau (MAPT). [provided by MGI curators] |