Primary Identifier | MGI:1341881 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 20974 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables SH2 domain binding activity. Involved in regulated exocytosis and regulation of synaptic vesicle priming. Located in synaptic vesicle. Is active in neuromuscular junction. Is expressed in several structures, including central nervous system; eye; and peripheral nervous system ganglion. Orthologous to human SYNGR3 (synaptogyrin 3). PHENOTYPE: Heterozygous knockout prevents the neurological phenotypes of pathogenic forms of microtubule-associated protein tau (MAPT). [provided by MGI curators] |