Primary Identifier | MGI:2685783 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 545192 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable calcium ion binding activity; phospholipid binding activity; and syntaxin binding activity. Involved in regulation of GABAergic synaptic transmission and regulation of behavior. Is active in GABA-ergic synapse. Is expressed in brain. Orthologous to human BAIAP3 (BAI1 associated protein 3). PHENOTYPE: Mice homozygous for a null allele are viable and fertile but exhibit increased PTZ-induced seizure propensity, as well as increased novelty-induced anxiety in both genders, with a more pronounced effect in females, and a faster developmentof tolerance to benzodiazepines in male mice. [provided by MGI curators] |