| Primary Identifier | MGI:96942 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 17229 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables heparin binding activity and peptidase activity. Predicted to be involved in proteolysis. Predicted to act upstream of or within inflammatory response. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including alimentary system; genitourinary system; immune system; lumbar vertebra; and skin. Orthologous to several human genes including TPSAB1 (tryptase alpha/beta 1). PHENOTYPE: Mice homozygous for a knock-out allele show reduced recruitment of eosinophils to sites of T. spiralis larvae and decreased elimination of larvae in chronically infected skeletal muscle. Mice homozygous for a knock-in allele show a reduced ability to clear K. pneumoniae from their peritoneal cavity. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
