Primary Identifier | MGI:1349391 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 26945 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in membrane. Predicted to be active in extracellular space. Orthologous to human TPSG1 (tryptase gamma 1). PHENOTYPE: Homozygous knockout affects lung parameters after methacholine challenge and reduces susceptibility to smoke-induced COPD and DSS-induced colitis. [provided by MGI curators] |