| Primary Identifier | MGI:1919356 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 72106 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including positive regulation of canonical NF-kappaB signal transduction; positive regulation of sprouting angiogenesis; and regulation of pyruvate kinase activity. Predicted to be located in endoplasmic reticulum lumen. Predicted to be active in nucleus. Is expressed in brain; gonad; lung; metanephros; and submandibular gland. Orthologous to human JMJD8 (jumonji domain containing 8). PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced capillaries in muscle tissue and reduced glycolysis in isolated cells. Mice for another null allele exhibit increased insulin sensitivity and glucose tolerance. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
