| Primary Identifier | MGI:105120 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 19252 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables mitogen-activated protein kinase binding activity and phosphoprotein phosphatase activity. Involved in negative regulation of MAPK cascade; negative regulation of cell population proliferation; and protein dephosphorylation. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; heart; limb; and sensory organ. Human ortholog(s) of this gene implicated in breast cancer. Orthologous to human DUSP1 (dual specificity phosphatase 1). PHENOTYPE: Homozygous mutant mice were viable, fertile, and showed no apparent morphological defects. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
