| Primary Identifier | MGI:1924378 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 77128 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within maternal behavior; negative regulation of glucocorticoid mediated signaling pathway; and positive regulation of prolactin signaling pathway. Located in nuclear body. Is expressed in blastocyst; early embryo; polar body; and uterus. Orthologous to human CREBRF (CREB3 regulatory factor). PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired social recognition, increased vertical and horizontal activity, abnormal maternal nurturing, decreased prolactin and corticosterone serum levels, and abnormal mammary gland growth during lactation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
