| Primary Identifier | MGI:1097161 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 12018 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables identical protein binding activity. Involved in cellular response to UV; positive regulation of apoptotic process; and release of cytochrome c from mitochondria. Acts upstream of or within several processes, including apoptotic signaling pathway; lymphocyte apoptotic process; and regulation of protein metabolic process. Located in cytosol; endoplasmic reticulum; and mitochondrial outer membrane. Part of BAK complex. Is expressed in several structures, including alimentary system; brain; branchial arch; genitourinary system; and hemolymphoid system gland. Human ortholog(s) of this gene implicated in ataxia telangiectasia and cervix carcinoma. Orthologous to human BAK1 (BCL2 antagonist/killer 1). PHENOTYPE: Homozygous mutation of this gene does not result in a phenotype. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
